Table 1.
Population characteristics and bacterial organisms
|
Characteristics |
Patients with PNTM disease (N=9) |
| Mean age, mean±SD (years) | 63±8 |
| Female gender, n (%) | 9 (100) |
| Ethnicity | |
| White, n (%) | 9 (100) |
| Never smokers, n (%) | 3 (33) |
| CFTR carriers, n (%) | 2 (22) |
| Scoliosis, n (%) | 3 (33) |
| Joint hypermobility, n (%) | 2 (22) |
| Positive thumb-wrist sign, n (%) | 1 (11) |
| Mitral valve prolapse, n (%) | 0 (0) |
| Cough, n (%) | 9 (100) |
| Bronchiectasis, n (%) | 9 (100) |
| Previous history of NTM-positive sputum, n (%) | 9 (100) |
| On NTM therapy at collection, n (%) | 5 (56) |
| Elevated inflammatory markers at collection, n (%) | 5 (56) |
| Macrolide exposure at collection, n (%) | 4 (44) |
| Immunomodulatory drugs, n % | 0 (0) |
| BMI, mean±SD | 20.8±3.2 |
| Mycobacteria, n (%) | |
| MAC | 4 (45) |
| MAB | 3 (33) |
| MAC & MAB | 2 (22) |
BMI, body mass index; CFTR, cystic fibrosis transmembrane conductance regulator; MAB, mycobacterium abscessus; MAC, mycobacterium avium complex; NTM, non-tuberculous mycobacteria.