TABLE 2.

Statistically significant differential recoding sites.

Chr:position	Gene	AA change	Δ editing	Pval (MW)	Padj (BH)
chr4:57976234*	IGFBP7	K95R	–0.417	0.000015	0.000016
chr13:46090371	COG3	I635V	–0.536	0.000016	0.000017
chr19:7585273	ZNF358	K382R	–0.381	0.000016	0.000017
chr1:160302244*	COPA	I164V	–0.416	0.000017	0.000018
chr4:57976286*	IGFBP7	R78G	–0.522	0.000019	0.000019
chrX:153579950*	FLNA	Q474R	–0.310	0.000027	0.000027
chr4:17805279	DCAF16	I162M	0.059	0.000088	0.000088
chr8:103841636	AZIN1	S367G	–0.081	0.000218	0.004633
chr20:36147572*	BLCAP	Y2C	0.090	0.000295	0.005015
chr20:36147563	BLCAP	Q5R	0.063	0.000178	0.005043
chr4:77979680	CCNI	R61G	–0.100	0.000132	0.005610
chr20:36147533	BLCAP	K15R	0.029	0.000464	0.005634
chr19:14593605	GIPC1	T62A	–0.237	0.000458	0.006488
chr12:133682596	ZNF140	Y142H	0.061	0.000998	0.010604
chr14:26917530	NOVA1	S363G	0.099	0.000128	0.010880
chr3:9876560	TTLL3	K419R	0.016	0.001442	0.011143
chr3:58141801*	FLNB	Q2103R	–0.228	0.001180	0.011144
chr5:156736808	CYFIP2	K124E	–0.007	0.001350	0.011475
chr15:75646086	NEIL1	K242R	0.182	0.001673	0.011850
chr4:77977164	CCNI	K123R	–0.009	0.002107	0.013777
chr1:12091858	MIIP	S355G	0.018	0.002867	0.017407
chr21:34922801*	SON	T422A	–0.146	0.003614	0.020479
chr3:58141791	FLNB	M2100V	–0.116	0.004256	0.022610
chr18:32825609	ZNF397	K314E	0.058	0.004582	0.022910
chr10:79397298	KCNMA1	S35G	–0.051	0.005179	0.024456
chr6:44120349*	TMEM63B	Q619R	–0.144	0.006899	0.030864

Per each position we report the target gene and amino-acid change induced by RNA editing, the difference between mean editing levels of groups, the Mann–Whitney p-value, and the adjusted p-value by Benjamin–Hochberg. Positive Δ values indicate higher editing in cerebellum than artery, while negative Δs are associated to lower editing in cerebellum than artery. Positions marked by * are differentially edited by also the Tran et al. statistical pipeline.