Table 3.
Characteristics of the 3 groups on index date
| Control (n = 300) | NPHPT (n = 11) | PHPT (n = 17) | P | |
|---|---|---|---|---|
| Female (%) | 214 (71) | 10 (92) | 15 (88) | .122 |
| Age, ya | 70 (20) | 68 (11) | 67 (6) | .975 |
| BMI (g/cm2)c | 25.6 (25.0, 26.3) | 30.1 (24.4, 34.0) | 26.2 (23.4, 28.9) | .303 |
| PTH (ng/L)c | 42.5 (40.8, 44.2) | 106.8 (86.9, 123.9) | 102.4 (89.0, 112.4) | < .001 |
| Adjusted calcium (mmol/L)b | 2.37 (0.08) | 2.55 (0.05) | 2.75 (0.11) | < .001 |
| Phosphate (mmol/L)b | 1.12 (0.18) | 1.04 (0.14) | 0.89 (0.16) | < .001 |
| Alkaline phosphatase (IU/L)a | 78 (37) | 98 (33) | 88 (27) | .070 |
| 25(OH)D (nmol/L)a | 78.9 (32.9) | 62.8 (23.5) | 71.4 (30.5) | .083 |
| Z score spineb | –0.1 (1.7) | 0.2 (2.2) | –0.2 (1.3) | .932 |
| Z score neckb | –0.4 (1.0) | –0.1 (1.3) | –0.4 (0.8) | .770 |
Results of pairwise comparisons: PTH in the control group differed significantly from both the NPHPT and PHPT groups, but there was no statistically significant difference between the NPHPT and PHPT groups. Adjusted calcium differed significantly between all groups. Phosphate differed significantly only between the PHPT and control group.
Abbreviations: 25(OH)D, 25-hydroxyvitamin D; BMI, body mass index; n, number of patients; NPHPT, normocalcemic hyperparathyroidism; PHPT: primary hyperparathyroidism; PTH, parathyroid hormone. Values in bold were significant.
aShown as median (interquartile range).
bShown as mean (SD).
cShown as geometric mean (95% CI).