Table 2.

Treatment-related adverse events.

Event	Gradea 1	Grade 2	Grade 3	Grade 4/5
	n (%)
Fever	22 (65)	1 (3)	0	0
Nausea	9 (26)	1 (3)	0	0
Musculoskeletal pain	8 (24)	1 (3)	1 (3)	0
Vomiting	6 (18)	0	0	0
Asthenia	5 (15)	3 (9)	1 (3)	0
Headache	3 (9)	0	0	0
Injection site reaction/erythema	2 (6)	0	0	0
Bradycardia	1 (3)	0	0	0
Diarrhea	1 (3)	1 (3)	0	0
Nail dyschromia	1 (3)	0	0	0
Local pain	1 (3)	0	0	0
Epigastric pain	1 (3)	1 (3)	0	0
Injection site reaction/swelling	1 (3)	0	0	0
Herpes labialis	1 (3)	0	0	0
Injection site reaction/hyperemia	1 (3)	0	0	0
Hypotension	1 (3)	0	0	0
Mild visus decrease	1 (3)	0	0	0
Loss of appetite	1 (3)	0	0	0
Agitation	1 (3)	0	0	0
Vertigo	1 (3)	0	0	0
Anemia	0	1 (3)	0	0
Abdominal pain	0	1 (3)	0	0
Neutropenia	0	1 (3)	0	0
Persistent coughing	0	1 (3)	0	0

^aGrades of adverse events were defined according to the National Cancer Institute CTCAE, version 4.0.