Table 3.
The enriched terms for DEGs.
| Category | Term | Description | Count | Genes | P-value |
|---|---|---|---|---|---|
| UP_KEYWORDS | / | Phosphoprotein | 57 | KDM6A, CXORF38, IQGAP1, ZBTB38, TOP1, NLRC4, ANK1, TPP2, ASMTL, KIAA1033, USP10, VPS13B, INO80D, AHNAK, ZFX, UBE2O, ACVR2B, KHSRP, FKBP15, SRCAP, KDM6B, BID, PLXNC1, AGFG1, STK11, SSFA2, HADHA, ZNF652, MYL9, CHD9, BCL11B, VPS35, BAZ2A, HECTD1, DHX9, TAOK1, EPRS, CD99, SAMHD1, DGKK, AFF3, MYLPF, AGER, CDC27, PTPN12, FXR1, SAFB2, HDAC5, ATRX, CYBA, B3GAT1, SON, FCGR2C, JAK1, MAP4, SMC1A, TOB1 | 6.04E-09 |
| GOTERM_MF_DIRECT | GO:0005515 | Protein binding | 57 | IQGAP1, ZBTB38, TOP1, NLRC4, AP1S2, ANK1, TPP2, ASMTL, TIA1, EIF1AX, USP10, NSMAF, AHNAK, CSF2RA, SLC25A6, HES1, UBE2O, ACVR2B, EREG, MED16, ZMIZ2, KHSRP, FKBP15, SRCAP, KDM6B, BID, IL1R2, PLXNC1, AGFG1, STK11, HADHA, ZNF652, BCL11B, VPS35, BAZ2A, HECTD1, DHX9, TAOK1, EPRS, SAMHD1, AGER, CDC27, PTPN12, FXR1, SAFB2, HDAC5, ATRX, CYBA, SON, FCGR2C, CSGALNACT2, JAK1, MAP4, RPL37A, SMC1A, IGFBP2, TOB1 | 1.72E-07 |
| UP_KEYWORDS | / | Methylation | 15 | DHX9, KDM6A, CXORF38, STK11, SLC25A6, MYLPF, EPRS, HADHA, SAFB2, ATRX, SON, ZMIZ2, BCL11B, KHSRP, AHNAK | 1.81E-05 |
| UP_KEYWORDS | / | Acetylation | 29 | BID, STK11, HADHA, IQGAP1, MYL9, CHD9, TOP1, TPP2, BCL11B, TIA1, KIAA1033, USP10, BAZ2A, AHNAK, DHX9, SLC25A6, SAMHD1, EPRS, PTPN12, SAFB2, FXR1, ATRX, HDAC5, SON, KHSRP, FKBP15, MAP4, JAK1, SMC1A | 2.33E-05 |
| UP_KEYWORDS | / | Ubl conjugation | 19 | BID, SSFA2, SAMHD1, SAFB2, ZBTB38, HDAC5, ATRX, CHD9, TOP1, UBE2O, SON, ZMIZ2, BCL11B, EIF1AX, KHSRP, MAP4, USP10, BAZ2A, AHNAK | 4.44E-05 |
| GOTERM_CC_DIRECT | GO:0005634 | Nucleus | 38 | KDM6A, STK11, SSFA2, ZNF652, IQGAP1, ZBTB38, CHD9, TOP1, NLRC4, ANK1, TPP2, BCL11B, USP10, INO80D, BAZ2A, AHNAK, HECTD1, DHX9, SLC25A6, ZFX, AFF3, SAMHD1, CDC27, SAFB2, ATRX, HES1, HDAC5, UBE2O, CYBA, ZMIZ2, MED16, PERM1, JAK1, RPL37A, SMC1A, SRCAP, KDM6B, TOB1 | 6.28E-05 |
| UP_KEYWORDS | / | Isopeptide bond | 15 | SSFA2, ZBTB38, SAFB2, ATRX, TOP1, CHD9, SON, ZMIZ2, TPP2, BCL11B, EIF1AX, KHSRP, MAP4, BAZ2A, AHNAK | 6.95E-05 |
| GOTERM_CC_DIRECT | GO:0005737 | Cytoplasm | 36 | BID, IL1R2, STK11, SSFA2, IQGAP1, CHD9, ANK1, TPP2, ASMTL, TIA1, USP10, NSMAF, BAZ2A, AHNAK, HECTD1, DHX9, TAOK1, DGKK, CD99, AFF3, EPRS, CDC27, PTPN12, FXR1, SAFB2, HES1, HDAC5, UBE2O, ACVR2B, FCGR2C, PERM1, CEMP1, JAK1, MAP4, SMC1A, TOB1 | 1.86E-04 |
| GOTERM_MF_DIRECT | GO:0044822 | Poly(A) RNA binding | 14 | DHX9, FXR1, SAFB2, TOP1, UBE2O, SON, EIF1AX, TIA1, KHSRP, MAP4, RPL37A, USP10, SMC1A, AHNAK | 4.98E-04 |
| UP_KEYWORDS | / | Chromatin regulator | 7 | ATRX, HDAC5, CHD9, KDM6A, SRCAP, BAZ2A, KDM6B | 7.22E-04 |
| UP_KEYWORDS | / | Nucleus | 33 | KDM6A, AGFG1, STK11, ZNF652, ZBTB38, CHD9, TOP1, TPP2, BCL11B, TIA1, USP10, BAZ2A, INO80D, AHNAK, DHX9, ZFX, SAMHD1, AFF3, CDC27, SAFB2, ATRX, HES1, HDAC5, UBE2O, SON, ZMIZ2, MED16, PERM1, KHSRP, SMC1A, SRCAP, KDM6B, TOB1 | 1.46E-03 |