Table 2.
Most differentially regulated genes in the cell culture systems used in this study.
| Sample | Locus tag | Function | Ratio (P-value) |
|---|---|---|---|
| Sample 6 (24 h in HL-60) vs. Sample 7 (48 h in ISE6) | HGE1_00140 | Hypothetical, localizes to morulae membrane (18) | 5.89 (0.045) |
| HGE1_05192 | p44-18 | 3.83 (0.008) | |
| HGE1_04712 | Phage repressor protein C | 3.92 (0.026) | |
| Sample 5 (HL-60 grown Ap exposed to ISE6) vs. Sample 1 (2 h with HL-60) | HGE1_05312 | Transcriptional regulator tr1 (at p44 expression locus) (19, 23, 24) | 9.94 (not done) |
| HGE1_02797 | Hypothetical | 6.06 (not done) | |
| HGE1_02157 | Single-stranded DNA-binding protein | 5.97 (not done) | |
| Sample 6 (24 h in HL-60 vs. 24 h in PMN (sample 8) | HGE1_01702 | tRNA-Arg | 7.561 (0.018) |
| HGE1_06226 | tRNA-Lys | 7.45 (0.050) | |
| HGE1_06206 | tRNA-Met | 5.36 (0.000) |
HL-60, human promyelocyte cells; ISE6, Ixodes scapularis tick cells; PMN, human granulocytes.