Fig. 5. A) 3D framework of Zn-cpon-1 and schematic illustration of its release process. B) (a) 5-FU released from Zn-cpon-1 in PBS at different temperatures. (b) Comparison of the release rate in different temperatures. (c) 5-FU released from Zn-cpon-1 in PBS with a change in pH. (d) Comparison of the release rate in different pH conditions. C) Schematic illustration of the synthetic procedures and DOX release of P@ZIF-8. D) Release behavior of DOX in a) 1 × 10–3 M GSH and b) 1 × 10–3 M H2O2 with the pH-dependent changes. Reprinted copyright from ACS, 2018 and Wiley, 2017.19,60 .
