Figure 1.

H₂S levels in the hearts of db/db mice. (A) CSE expression in the cardiac tissues of db/db mice. (B) Fluorescence microscopy was used to detect H₂S levels in cardiac tissues with the fluorescent probe 7-azido-4-methyl-coumarin (C-7Az). (C) CSE expression in neonatal rat cardiomyocytes (NRCMs) treated with high glucose, palmitate, and oleate. (D) H₂S levels were examined at 12, 24, and 48 hours with the fluorescent probe C-7Az. Values are presented as the mean± SD from n=6 replicates. *p<0.05, **p<0.01, ***p<0.001 vs control group, ##p<0.01, ###p<0.001 vs db/db group or HG+Pal+Ole group.