Table 3.
List of all VMEs and MEs with RAST for each species/agent combination and incubation time and the corresponding reference categorizationa
Species | Isolate | Antimicrobial agent | Error | Incubation time (h) | RAST zone/ interpretationb |
Reference |
Standard disc diffusion discrepant from MIC | Agar manufacturer | |||
---|---|---|---|---|---|---|---|---|---|---|---|
4 h | 6 h | 8 h | disc diffusion | MIC | |||||||
E. coli | A | TZP | ME | 4 | 6/R | 16/ATU | 19/ATU | — | S | BD BBL | |
TZP | ME | 4 | 6/R | 16/ATU | 17/ATU | — | S | Oxoid | |||
CTX | ME | 4 | 6/R | 19/S | 21/S | — | S | BD BBL | |||
CTX | ME | 4 | 6/R | 20/S | 19/S | — | S | Oxoid | |||
CAZ | ME | 4 | 6/R | 18/S | 18/S | — | S | BD BBL | |||
CAZ | ME | 4 | 6/R | 18/S | 19/S | — | S | Oxoid | |||
B | TZP | ME | 4 | 6/R | 19/ATU | 19/ATU | — | S | BD BBL | ||
TZP | ME | 4 | 6/R | 18/ATU | 19/ATU | — | S | Oxoid | |||
CTX | ME | 4 | 6/R | 20/S | 19/S | — | S | BD BBL | |||
CTX | ME | 4 | 6/R | 19/S | 20/S | — | S | Oxoid | |||
CAZ | ME | 4 | 6/R | 21/S | 19/S | — | S | BD BBL | |||
CAZ | ME | 4 | 6/R | 19/S | 19/S | — | S | Oxoid | |||
C | TZP | ME | 4 | 12/R | 15/ATU | 15/ATU | — | S | BD BBL | ||
D | TZP | ME | 4 | 6/R | 16/ATU | 17/ATU | — | S | Oxoid | ||
E | CTX | ME | 4 | 10/R | 19/S | 21/S | — | S | BD BBL | ||
F | TOB | VME | 4 | 14/S | 14/ATU | 14/ATU | — | R | I | BD BBL | |
K. pneumoniae | G | AMK | ME | 4 | 12/R | 13/ATU | 13/S | — | S | I | Oxoid |
H | GEN | VME | 8 | 13/ATU | 13/ATU | 14/S | — | R | I | BD BBL | |
P. aeruginosa | I | IPM | ME | 6 | — | 6/R | 19/S | — | S | BD BBL | |
IPM | ME | 6 | — | 6/R | 18/S | — | S | Oxoid | |||
J | TZP | VME | 6 | — | 17/S | 15/ATU | — | R | BD BBL | ||
S. aureus | K | NOR | ME | 6 | — | 6/R | 15/S | S | — | Oxoid | |
L | NOR | VME | 6 | — | 14/S | 14/ATU | R | — | BD BBL | ||
E. faecium | M | AMP | ME | 6 | — | 6/R | 9/S | — | S | R | BD BBL |
AMP | ME | 6, 8 | — | 6/R | 6/R | — | S | R | Oxoid | ||
S. pneumoniae | N | SXT | ME | 4 | 6/R | 15/S | 15/S | — | S | BD BBL | |
SXT | ME | 4 | 6/R | 14/S | 15/S | — | S | Oxoid | |||
O | SXT | ME | 4, 6, 8 | 6/R | 6/R | 6/R | — | S | R | BD BBL | |
SXT | ME | 4, 6, 8 | 6/R | 6/R | 6/R | — | S | I | Oxoid | ||
P | NOR | VME | 4, 6, 8 | 12/S | 14/S | 13/S | R | — | BD BBL | ||
NOR | VME | 4, 6, 8 | 11/S | 12/S | 12/S | R | — | Oxoid | |||
Q | NOR | VME | 6, 8 | NG | 14/S | 13/S | R | — | BD BBL | ||
NOR | VME | 6, 8 | NG | 13/S | 13/S | R | — | Oxoid | |||
R | NOR | VME | 8 | NG | NG | 13/S | R | — | BD BBL | ||
NOR | VME | 8 | NG | 11/ATU | 12/S | R | — | Oxoid |
AMK, amikacin; AMP, ampicillin; CAZ, ceftazidime; CTX, cefotaxime; IPM, imipenem; GEN, gentamicin; NOR, norfloxacin; SXT, trimethoprim/sulfamethoxazole; TOB, tobramycin; TZP, piperacillin/tazobactam; NG, no growth; Oxoid, from Thermo Fisher Scientific; BD BBL, from BD. A dash in either of the ‘Reference’ columns indicates that method is not used as a reference.
A single isolate may show several errors and some errors are with both MH manufacturers.
Erroneous interpretations are shown in bold.