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. 2020 Feb 4;75(4):968–978. doi: 10.1093/jac/dkz548

Table 3.

List of all VMEs and MEs with RAST for each species/agent combination and incubation time and the corresponding reference categorizationa

Species Isolate Antimicrobial agent Error Incubation time (h) RAST zone/ interpretationb
Reference
Standard disc diffusion discrepant from MIC Agar manufacturer
4 h 6 h 8 h disc diffusion MIC
E. coli A TZP ME 4 6/R 16/ATU 19/ATU S BD BBL
TZP ME 4 6/R 16/ATU 17/ATU S Oxoid
CTX ME 4 6/R 19/S 21/S S BD BBL
CTX ME 4 6/R 20/S 19/S S Oxoid
CAZ ME 4 6/R 18/S 18/S S BD BBL
CAZ ME 4 6/R 18/S 19/S S Oxoid
B TZP ME 4 6/R 19/ATU 19/ATU S BD BBL
TZP ME 4 6/R 18/ATU 19/ATU S Oxoid
CTX ME 4 6/R 20/S 19/S S BD BBL
CTX ME 4 6/R 19/S 20/S S Oxoid
CAZ ME 4 6/R 21/S 19/S S BD BBL
CAZ ME 4 6/R 19/S 19/S S Oxoid
C TZP ME 4 12/R 15/ATU 15/ATU S BD BBL
D TZP ME 4 6/R 16/ATU 17/ATU S Oxoid
E CTX ME 4 10/R 19/S 21/S S BD BBL
F TOB VME 4 14/S 14/ATU 14/ATU R I BD BBL
K. pneumoniae G AMK ME 4 12/R 13/ATU 13/S S I Oxoid
H GEN VME 8 13/ATU 13/ATU 14/S R I BD BBL
P. aeruginosa I IPM ME 6 6/R 19/S S BD BBL
IPM ME 6 6/R 18/S S Oxoid
J TZP VME 6 17/S 15/ATU R BD BBL
S. aureus K NOR ME 6 6/R 15/S S Oxoid
L NOR VME 6 14/S 14/ATU R BD BBL
E. faecium M AMP ME 6 6/R 9/S S R BD BBL
AMP ME 6, 8 6/R 6/R S R Oxoid
S. pneumoniae N SXT ME 4 6/R 15/S 15/S S BD BBL
SXT ME 4 6/R 14/S 15/S S Oxoid
O SXT ME 4, 6, 8 6/R 6/R 6/R S R BD BBL
SXT ME 4, 6, 8 6/R 6/R 6/R S I Oxoid
P NOR VME 4, 6, 8 12/S 14/S 13/S R BD BBL
NOR VME 4, 6, 8 11/S 12/S 12/S R Oxoid
Q NOR VME 6, 8 NG 14/S 13/S R BD BBL
NOR VME 6, 8 NG 13/S 13/S R Oxoid
R NOR VME 8 NG NG 13/S R BD BBL
NOR VME 8 NG 11/ATU 12/S R Oxoid

AMK, amikacin; AMP, ampicillin; CAZ, ceftazidime; CTX, cefotaxime; IPM, imipenem; GEN, gentamicin; NOR, norfloxacin; SXT, trimethoprim/sulfamethoxazole; TOB, tobramycin; TZP, piperacillin/tazobactam; NG, no growth; Oxoid, from Thermo Fisher Scientific; BD BBL, from BD. A dash in either of the ‘Reference’ columns indicates that method is not used as a reference.

a

A single isolate may show several errors and some errors are with both MH manufacturers.

b

Erroneous interpretations are shown in bold.