Table 3.
Rate of Caffeine Quantified in the Receptor Fluid at 15 mins, 1 hr and 2 hrs Under Neutral Conditions
| Caffeine % in Basolateral Compartment Compared to the Dose Applied | |||
|---|---|---|---|
| 15 mins | 1 hr | 2 hrs | |
| Negative Control | 18.0 ± 0.6 | 30.6 ± 0.1 | 24.7 ± 1.8 |
| Vaseline | 0.0 ± 0.0* | 0.0 ± 0.0* | 0.0 ± 0.0* |
| Device A | 0.1 ± 0.0 | 3.5 ± 0.0 | 7.0 ± 0.0 |
| Device B | 0.2 ± 0.0 | 5.3 ± 0.0 | 8.6 ± 0.1 |
| Device C | 0.1 ± 0.0 | 3.5 ± 0.0 | 7.5 ± 0.0 |
Note: *Value below 0.1 μg.