Skip to main content
. 2016 Apr 3;2016(4):CD011946. doi: 10.1002/14651858.CD011946.pub2

Grimes 2014.

Methods A prospective, randomised, double‐blind, controlled, multicentre cross‐over study
Participants Participants were required to have at least 4 acne scars in the facial area that met the following criteria: soft‐contoured, rolling scars that were distensible and moderate to severe (3 or 4) on a validated 4‐point (1 ‐ 4) acne scar rating scale (ASRS)
Interventions Participants were randomised to receive either PMMA‐collagen or control injections of saline. At month 6, those who had received control injections could be treated with PMMA‐collagen
Outcomes Participants were deemed responders if 50% or more of their scars improved by at least 2 grades on the ASRS by both investigators and participants self assessments
 Visits were scheduled every 2 weeks for the first month, then at month 3 and 6. All participants were followed for an additional 6 months after cross‐over
Notes Abstract only. Abstract does not contain enough information for 'Risk of bias' assessment and completion of the Characteristics of included studies table