Table 3.

General and Disease-Specific HRQoL – Changes Over Time

	All				CHF				COPD
	Baseline	+1 month	+6 months	+12 months	Baseline	+1 month	+6 months	+12 months	Baseline	+1 month	+ 6 months	+12 months
EQ-5D index	0.53	0.57	0.53	0.46
EQ-5D VAS	50.4	54.1*	50.7	53.0
RAND-36
PF	20.7	20.8	20.4	18.6
RP	10.8	20.0*	22.4***	18.7
BP	55.4	62.2*	55.8	56.0
GH	38.2	42.6*	43.5*	42.0
VT	41.4	43.2	46.6*	42.6
SF	51.6	61.0***	60.3***	62.0***
RE	40.5	55.8*	57.4***	55.5*
MH	60.4	67.5***	69.4***	66.5*
MLHFQ Score					42.6	36.2*	39.3	40.3
MLHFQ Physical					20.4	19.4	21.9	21.2
MLHFQ Emotional					9.0	7.5*	8.2	8.7
SGRQ Symptom									57.2	50.9*	52.9	57.5
SGRQ Activity									78.4	80.8	82.5	84.8***
SGRQ Impact									46.6	49.2	47.4	50.9*
SGRQ Total									59.4	58.9	58.9	62.7

Notes: Results are presented as means. P-values are from GEE regression analysis. P-value vs baseline is indicated; *p < 0.05; ***p < 0.001.

Abbreviations: BP, bodily pain; CHF, chronic heart failure; COPD, chronic obstructive pulmonary disease; GEE, Generalized Estimating Equations; GH, general health; HRQoL, health-related quality of life; MLHFQ, Minnesota Living with Heart Failure Questionnaire; MH, mental health; PF, physical functioning; RE, role-emotional; RP, role-physical; SF, social functioning; SGRQ, St. Georges Respiratory Questionnaire; VT, vitality.