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Effects of PEG content of the polymer backbone on NCs size (A), zeta potential (B), encapsulation efficiency (C) and HK in vitro release (D). Values are mean ± SD for (n = 3). For (A–C), *p < 0.05, **p < 0.01, ***p < 0.001 compared with 5% PEG-PLGA (F1). Δp < 0.05 compared with 10% PEG-PLGA (F4).
