Table 2.
Logistic Analysis of Exosomal MicroRNA Profile and Diagnostic Performance of Patients with HCC Compared with Control Group
Exosomal MicroRNA Group | AUC | Univariate | Multivariate | ||
---|---|---|---|---|---|
P value | HR | 95% CI | P value | ||
miRNA-21 | 0.912 | 0.001 | 0.076 | 0.024–0.241 | 0.001 |
miRNA-96 | 0.802 | 0.001 | 0.108 | 0.016–0.832 | 0.038 |
miRNA-122 | 0.853 | 0.001 | 0.115 | 0.027–0.903 | 0.043 |
Notes: Control group includes healthy participants, patients with cirrhosis. logit(P=HCC)= −2.275–0.258×miR-122–2.109×miR-21−1.796×miR-96.
Abbreviations: CI, confidence interval; AUC, area under the receiver operating characteristic curve; HR, hazard risk; HCC, hepatocellular carcinoma.