Table 4.
Univariate and Multivariate Analysis of Factors Associated with Survival
| Overall Survival | Disease-Free Survival | |||||
|---|---|---|---|---|---|---|
| Univariate Analyses | Multivariate Analyses | Univariate Analyses | Multivariate Analyses | |||
| P | HR (95% CI) | P | P | HR (95% CI) | P | |
| Age (≤60 vs >60 y) | 0.361 | 0.145 | 0.288 | |||
| Sex (male vs female) | 0.896 | 0.798 | 0.386 | 0.299 | ||
| BMI, kg/m2 (≤25 vs >25) | 0.160 | 0.117 | 0.024 | 2.997 (1.365–6.583) | 0.006 | |
| ASA score (≤III vs >III) | 0.028 | 0.094 | 0.134 | 0.088 | ||
| Surgical approach (SBTS vs ES) | 0.036 | 3.268 (1.253–8.547) | 0.015 | 0.211 | ||
| Location of tumor (right vs left) | 0.614 | 0.924 | ||||
| pT (T3 vs T4) | 0.041 | 3.425 (1.337–8.773) | 0.010 | 0.964 | ||
| pN (N- vs N+) | 0.480 | 0.292 | ||||
| Stage of tumor (≤II vs >II) | 0.217 | 0.165 | ||||
| Tumor deposit (- vs +) | 0.007 | 4.116 (1.694–10.001) | 0.002 | <0.001 | 2.855 (1.397–5.834) | 0.004 |
| PNI (- vs +) | 0.031 | 2.678 (1.088–6.592) | 0.032 | <0.001 | 4.154 (1.941–8.891) | <0.001 |
| LVI | 0.050 | 0.208 | 0.256 | |||
Abbreviations: HR, hazard ratio; BMI, body mass index; ASA, American Society of Anesthesiologists; ES, emergency surgery; SBTS, stent as bridge to surgery; PNI, perineural invasion; LVI, lymphovascular invasion.