Summary of findings for the main comparison. Health education interventions to promote early presentation and referral for women with symptoms of endometrial cancer.

Health education interventions to promote early presentation and referral for women with symptoms of endometrial cancer
Patient or population: adult women with symptoms of endometrial cancer Settings: individual‐ or community‐level settings Intervention: any types of health education intervention Comparison: head‐to‐head intervention or a control (presumably usual/standard practice)
Outcomes	Illustrative comparative risks* (95% CI)		Relative effect (95% CI)	No of participants (studies)	Certainty of the evidence (GRADE)	Comments
	Assumed risk	Corresponding risk
	Control	Intevention
Overall survivala	No included study
Disease‐free survivalb	No included study
Delayed referralc	No included study
Delayed presentationd	No included study
Referral time (days)e	No included study
Presentation time (days)f	No included study
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: confidence interval
aSurvival until death from all causes. bSurvival until the appearance of a new lesion of disease. cTime from primary care first appointment to time of primary care referral to secondary care of longer than 14 days. dTime from symptom of postmenopausal bleeding to the first appointment with a responsible specialist of longer than 14 days and longer than three months for irregular bleeding if premenopausal. eTime from primary care first appointment to time of primary care referral to secondary care. fTime from symptom onset to arrival at primary care hospital.
GRADE Working Group grades of evidence High‐certainty: we are very confident that the true effect lies close to that of the estimate of the effect. Moderate‐certainty: we are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different. Low‐certainty: our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect. Very low‐certainty: we have very little confidence in the effect estimate: the true effect is likely to be substantially different from the estimate of effect.