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. 2020 Mar 13;6(11):eaax8429. doi: 10.1126/sciadv.aax8429

Fig. 3. Expression of proinflammatory mediators in skin and draining lymph nodes is reduced in Recruitment-MP–treated long-term surviving allografts.

Fig. 3

Relative mRNA expression in (A) skin samples and (B) draining lymph nodes from rejecting hindlimb allografts (N = 9 for skin and N = 11 for draining lymph nodes) or Recruitment-MP–treated long-term surviving allografts (N = 5 for skin and draining lymph nodes). Expression levels are presented as fold changes (2−ΔΔCt) relative to naïve skin (N ≥ 6) or nondraining lymph nodes (N = 7 to 9). Bars represent means ± SD, and dots represent values from individual rats. Groups were compared by Welch’s t test or Mann-Whitney U test, as appropriate, and significant differences are indicated by *P < 0.05, **P < 0.01, or ***P < 0.001.