Key resources table.
| Reagent type (species) or resource |
Designation | Source or reference | Identifiers | Additional information |
|---|---|---|---|---|
| Antibody | Rabbit monoclonal anti-cyclin D1 | Cell Signaling | Cat.# 55506, RRID:AB_2827374 | IHC-1/200 |
| Antibody | Rabbit polyclonal anti-Maf | Santa Cruz Biotechnology |
Cat.#sc-7866, RRID:AB_638562 | IHC-1/200 |
| Antibody | Mouse monoclonal anti-Ecadherin | BD | Cat.#610181, RRID:AB_397580 | IHC-1/500 |
| Antibody | Rabbit monoclonal anti-Erk | Cell Signaling | Cat.# 4695, RRID:AB_390779 | WB-1/2000 |
| Antibody | Mouse monoclonal anti-Foxe3 | Santa Cruz Biotechnology | Cat.#sc-377465 | IHC-1/200 |
| Antibody | Rabbit polyclonal anti-Jag1 | Santa Cruz Biotechnology | Cat.#sc-8303,RRID:AB_649685 | IHC-1/200, WB-1/500 |
| Antibody | Mouse monoclonal anti-Ki67 | BD | Cat.#550609, RRID:AB_393778 | IHC-1/200 |
| Antibody | Rabbit monoclonal Lamin A/C | Abcam | Cat.# ab133256, RRID:AB_2813767 | IHC-1/1000 |
| Antibody | Rabbit monoclonal Notch1 | Cell Signalling | Cat.#4380, RRID:AB_10691684 | WB-1/1000 |
| Antibody | Rabbit monoclonal Notch1-ICD | Cell Signaling | Cat.#4147, RRID:AB_2153348 | IHC-1/200 |
| Antibody | Rabbit polyclonal anti-Prox1 | Covance | Cat.#PRB-238C, RRID:AB_291595 | IHC-1/200 |
| Antibody | Rabbit polyclonal anti-pHH3 | Millipore | Cat.#06-570, RRID:AB_310177 | IHC-1/200 |
| Antibody | Rabbit anti-pS6 | Cell Signaling | Cat.#5364, RRID:AB_10694233 | IHC-1/200 |
| Antibody | Rabbit monoclonal anti-pmTOR | Cell Signaling | Cat.#5536, RRID:AB_10691552 | IHC-1/200 |
| Antibody | Rabbit polyclonal anti-Pax6 | Covance | Cat.#PRB-278P, RRID:AB_291612 | IHC-1/200 |
| Antibody | Rabbit anti-p4EBP1 | Cell Signaling | Cat.#2855, RRID:AB_560835 |
IHC-1/200 |
| Antibody | Rabbit monoclonal anti-pERK | Cell Signaling | Cat.#9101, RRID:AB_331646 | IHC-1/200 |
| Antibody | Mouse monoclonal anti-pERK | Santa Cruz Biotechnology |
Cat# sc-7383, RRID:AB_627545 | WB-1/1000 |
| Antibody | Rabbit polyclonal anti-α-Crystallin | Sam Zigler (National Eye Institute) | IHC-1/5000 | |
| Antibody | Rabbit polyclonal anti-γ-Crystallin | Sam Zigler (National Eye Institute) | IHC-1/5000 | |
| EdU | DNA synthesis monitoring probe | Abcam | cat. # ab14618 | |
| Commercial assay Kit | Click IT EdU Cell proliferation kit | Invitrogen | cat. # C10337 | |
| Commercial assay Kit | In situ cell death detection kit | Roche | cat.# 1168479510 | |
| Peptide, recombinant protein | recombinant murine FGF2 | ScienCell | cat.# 124-02 | |
| Genetic reagent (M. musculus) | Etv1flox | PMID:12741988 | MGI:2663693 | Dr. Silvia Arber (University of Basel, Basel, Switzerland) |
| Genetic reagent (M. musculus) | Etv4-/- | PMID:11094084 | MGI:2445834 | Dr. Xin Sun (University of California at San Diego, San Diego, CA) |
| Genetic reagent (M. musculus) | Etv5flox | PMID:19386269 | MGI:3849047 | Dr. Xin Sun (University of California at San Diego, San Diego, CA) |
| Genetic reagent (M. musculus) | Tsc1flox | PMID:12205640 | MGI:2656240 | Dr. Stephen Tsang (Columbia University, New York, NY) |
| Genetic reagent (M. musculus) | R26EtvEnR | PMID:19386268 | MGI:3848910 | Drs. Andrew McMahon (University of Southern California, Los Angeles, CA) and James Li (University of Connecticut Health Center, Farmington, CT) |
| Genetic reagent (M. musculus) | Map2k1flox | PMID:16887817 | MGI:3714918 | |
| Genetic reagent (M. musculus) | Map2k2KO | PMID:12832465 | MGI:2668345 | |
| Genetic reagent (M. musculus) | Mapk3-/- | PMID:11160759 | MGI:3042006 | |
| Genetic reagent (M. musculus) |
Mapk1flox | PMID:18596172 | MGI:3803954 | |
| Genetic reagent (M. musculus) | Fgf3OVE391 | PMID:7539358 | MGI:6393977 | Dr. Michael Robinson, Miami University. |
| Genetic reagent (M. musculus) | Pax6Le-Cre | PMID:11069887 | MGI:3045795 | |
| Genetic reagent (M. musculus) | Fgfr1flox | PMID:16421190 | Stock #: 007671 MGI:3713779 |
|
| Genetic reagent (M. musculus) | Fgfr2flox | PMID:12756187 | MGI:3044679 | Dr. David Ornitz, Washington University Medical School, St Louis, MO |