Skip to main content
. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Eur J Neurosci. 2019 Oct 6;51(3):742–754. doi: 10.1111/ejn.14580

Figure 1 – Schematic of morphine withdrawal model.

Figure 1 –

Equal volume (0.1 mL/10 g) saline or 10mg/kg morphine subcutaneously (s.c.) was injected and 1 mg/kg naloxone s.c. was injected 2 hours later. This paradigm was repeated for a total of 3 days. Subsequently animals experienced forced abstinence for 6 weeks, prior to behavioral testing.