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Fabricated ductal T-MOC platform. (A) Photograph of a fabricated dT-MOC. (B) Brightfield micrographs showing the formation of the lumen structure with a distinct epithelial lining at Day 4. Scale bar is 250 μm. Zoom-in image of boxed area in (B) showing distinct epithelial lining of PCCs. Scale bar is 20 μm. (C) Confocal micrograph of a cancer cell duct on a typical dT-MOC. (D) Immunohistology micrograph showing H&E and BrdU stainings.
