Fig. 1.

Comparison of serum CXCL13 levels among healthy controls (HC), low risk (LR) pSS, moderate risk (MR) pSS and pSS with non-Hodgkin lymphoma (pSS-NHL+) patients at visit 1. Serum CXCL13 levels were higher in all pSS patients when compared with HC (p < 0.0001). CXCL13 levels were lower in the low risk group when compared with the moderate risk (p < 0.0001) and the pSS-NHL+ group (p = 0.0008) but not significantly different between the pSS-NHL+ and the moderate risk group. Comparisons of CXCL13 concentrations among groups were performed using the Kruskal–Wallis test. The boxes show the median CXCL13 concentration and the quartiles Q1 and Q3. Each dot represents an individual patient. The values beyond the whiskers are outliers. The analysis included all values including these outliers