Table 1.
Patient # | Age | Diagnosis–stage | Conditioning regimen | Donor type/gender match | GvHD prophylaxis |
---|---|---|---|---|---|
1 | 58 | PMF–acceleration | FBM | MUD m to m | ATG, CyA, MMF |
2 | 50 | AML–1st CR | treo/flud | MUD m to m | ATG, CyA, MTX |
3 | 21 | AML–3rd PR | thio/flud | MMUD m to m | everolimus |
4 | 62 | CLL–Richter’s transformation | FBM | MUD f to m | ATG, CyA, MTX |
5 | 41 | AML–2nd CR | FBM | MRD f to f | CyA, MTX |
6 | 44 | AML–1st CR | FBM | MUD m to f | ATG, CyA, MTX |
7 | 54 | sAML–1st CR | FTM | MRD m to f | CyA, MTX |
8 | 44 | AML–1st CR | FTM | MUD m to f | ATG, tacrolimus, MMF |
9 | 51 | FL & CTLC–3rd PR | FTM | MRD f to f | CyA, MTX |
10 | 40 | ALL, Ph+–CR | flud/8 Gy TBI | MRD m to m | CyA, MTX |
11 | 49 | MM–SD | thio/treo/flud | MUD f to f | tacrolimus, MTX |
Median | 49 |
PMF, primary myelofibrosis; (s)AML, (secondary) acute myeloid leukemia; CLL, chronic lymphocytic leukemia; FL, follicular lymphoma; CTLC, cutaneous T cell lymphoma; ALL, acute lymphoblastic leukemia; MM, multiple myeloma; FBM, fludarabine/busulfan/melphalan; FTM, fludarabine/thiotepa/melphalan; treo, treosulfan; flud, fludarabine; thio, thiotepa; TBI, total body irradiation; MRD, matched related donor; MUD, matched unrelated donor; MMUD, mismatch unrelated donor; m, male; f, female; ATG, anti-thymocyte globulin; CyA, cyclosporine; MMF, mycophenolate; MTX, methotrexate