Table 1.
Relative abundances of bacterial taxa in adult mice born to influenza virus-infected mothers (MIA), or mock, and prepubertally (P28) treated with antibiotics, or vehicle.
| Taxa (family level) | mock – vehicle | MIA – vehicle | mock – antibiotic | MIA – antibiotic | p value |
|---|---|---|---|---|---|
| Erysipelotrichaceae | 0.0022 ± 0.00031 | 0.0067 ± 0.00069 | 0.0056 ± 0.0014 | 0.0046 ± 0.0005 | 0.0005 |
| Eubacteriaceae | 0.00014 ± 0.0001 | 0.0015 ± 0.00038 | 0.0022 ± 0.00056 | 0.0004 ± 0.00022 | 0.0007 |
| Porphyromonadaceae | 0.053 ± 0.0052 | 0.065 ± 0.0069 | 0.045 ± 0.0068 | 0.044 ± 0.0028 | 0.0042 |
| Carnobacteriaceae | 0.00016 ± 0.0002 | N.D. | 0.0011 ± 0.00044 | N.D. | 0.0047 |
| Marinilabiaceae | 0.0020 ± 0.0006 | 0.0044 ± 0.0010 | 0.0017 ± 0.00035 | 0.0005 ± 0.00022 | 0.0073 |
| Coriobacteriaceae | 0.0016 ± 0.00025 | 0.00058 ± 0.0002 | 0.0013 ± 0.00019 | 0.0011 ± 0.00023 | 0.014 |
| Peptococcaceae | 0.0042 ± 0.00070 | 0.0023 ± 0.00031 | 0.0019 ± 0.00048 | 0.0042 ± 0.00066 | 0.014 |
| Clostridiales Incertae Sedis IV | 0.0039 ± 0.00093 | 0.0017 ± 0.00037 | 0.00071 ± 0.00037 | 0.0015 ± 0.00038 | 0.015 |
| Flavobacteriaceae | 0.0021 ± 0.00014 | 0.0021 ± 0.00014 | 0.0016 ± 0.00024 | 0.0015 ± 0.00016 | 0.018 |
| Heliobacteriaceae | 0.0018 ± 0.00014 | 0.0018 ± 0.00022 | 0.0026 ± 0.00048 | 0.0014 ± 0.00019 | 0.022 |
| Lactobacillaceae | 0.024 ± 0.0057 | 0.0094 ± 0.0013 | 0.0129± 0.0025 | 0.0086 ± 0.0019 | 0.023 |
| Clostridiales Incertae Sedis XII | 0.0016 ± 0.00011 | 0.0016± 0.00020 | 0.0026 ± 0.00030 | 0.0021 ± 0.00013 | 0.024 |
| Clostridiales Incertae Sedis XI | 0.00054 ± 0.00021 | 0.0020 ± 0.00054 | 0.00089 ± 0.00023 | 0.0021 ± 0.00051 | 0.025 |
| Anaeroplasmataceae | N.D. | 0.010 ± 0.0035 | 0.055 ± 0.018 | 0.030 ± 0.015 | 0.028 |
| Aerococcaceae | N.D. | 0.00069 ± 0.0002 | 0.00016 ± 0.0001 | 0.00013 ± 0.0001 | 0.033 |
| Candidatus (saccharibacteria) | 0.00062 ± 0.00034 | 0.0024 ± 0.00056 | 0.00055 ± 0.00029 | 0.0029 ± 0.00084 | 0.035 |
| Clostridiales Incertae Sedis | 0.0043 ± 0.0010 | 0.0018 ± 0.00013 | 0.0024 ± 0.00047 | 0.0035 ± 0.00058 | 0.039 |
| Flammeovirgaceae | 0.0010 ± 0.00034 | 0.00015 ± 0.0001 | 0.00013 ± 0.0001 | N.D. | 0.042 |
| Piscirickettsiaceae | 0.00029 ± 0.00019 | 0.00085 ± 0.0003 | 0.055 ± 0.018 | 0.00014 ± 0.0001 | 0.052 |
| Ruminococcaceae | 0.10 ± 0.004 | 0.12 ± 0.004 | 0.11 ± 0.005 | 0.10 ± 0.005 | 0.07 |
| Micrococcaceae | 0.00038 ± 0.00019 | 0.00009 ± 0.003 | 0.00012 ± 0.00036 | N.D. | 0.11 |
| Cryomorphaceae | 0.0010 ± 0.00020 | 0.00079 ± 0.0002 | 0.00096 ± 0.00018 | 0.00056 ± 0.0001 | 0.20 |
| Synergistaceae | 0.0024 ± 0.00014 | 0.0015 ± 0.00028 | 0.0018 ± 0.00049 | 0.0019 ± 0.00037 | 0.23 |
Taxa are listed in order of significance (Kruskal-Wallis test). All values are presented as mean ± s.e.m. N.D., not detected.