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. 2020 Mar 13;10:4640. doi: 10.1038/s41598-020-61494-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Inhibitory effect of methanol extract of Centella asiatica on SR. (A) Sensorgram of CA extract binding with immobilized SR, (B) Dose-dependent SR inhibition by CA extract. Curves represent positive control (▼), 20 μg/ml (●), 40 μg/ml (■). Data are presented as mean ± SD and (C) Inhibitory effect of eluted compound (EC) on SR activity. The assay was carried out with five and seven μl column eluent. Data are presented as mean ± SD.