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Differences in the AUC (ΔAUC) in (a) analgesia, (b) hypothermia, (c) catalepsy and (d) immobility after each dose of Δ9‐THC or vehicle injection in the four genotypes of mice. *P < .05, as compared to WT mice. (e–h) The effects of pretreatment with AM251, AM630 or CID16020046 on Δ9‐THC‐induced tetrad in WT mice (n = 8 per group). # P < .05, as compared to the baseline before Δ9‐THC injection in each group; *P < .05, as compared to “Veh + Δ9‐THC” group
