FIGURE 3.

Effect of methacholine and L‐NAME on blood pressure and superior mesenteric artery blood flow WT and ENT4‐KO mice. Mice were given a bolus dose of either 1 µg/kg methacholine (MCh; a, b) or 60 mg/kg L‐NAME (c, d) and blood pressure and superior mesenteric artery (SMA) blood flow was measured. Each bar represents the mean ± SEM from 6 male WT, 8 female WT, 7 male ENT4‐KO, and 7 female ENT4‐KO mice. *Significant difference between the indicated groups (two‐way ANOVA with Bonferroni multiple comparison test, p < .05)