Participant mean baseline characteristics and trends across quartiles of sphingolipids among 4206 CHS (Cardiovascular Health Study) participants. *Measured in 1992 to 1993 for all participants. The colored graphics show means or percentages of each characteristic across quartiles of each of the sphingolipids. Unadjusted linear and logistic regression models were used to assess statistically significant (P<0.0022; 0.05/23 characteristics) associations of log‐transformed sphingolipids with each characteristic; statistically significant positive trends are blue, statistically significant negative trends are red, and gray indicates P>0.0022. Cer‐16 indicates ceramide with palmitic acid; Cer‐20, ceramide with arachidic acid; Cer‐22, ceremide with behenic acid; Cer‐24, ceremide with lignoceric acid; CRP, C‐reactive protein; HDL, high‐density lipoprotein; HF, heart failure; LDL, low‐density lipoprotein; LV, left ventricle; MI, myocardial infarction; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide; Q1, quartile 1 (the mean or percentage of each characteristic among participants with a sphingolipid level in the lowest 25% of the distribution); Q4, quartile 4 (the mean or percentage among participants with a sphingolipid level in the highest 25% of the distribution); SM‐16, sphingomyelin with palmitic acid; SM‐20, sphingomyelin with arachidic acid; SM‐22, sphingomyelin with behenic acid; SM‐24, sphingomyelin with lignoceric acid.