Table 4.

Association of Cancer With Outcome After Discharge

	Unadjusted Models, Cancer vs. No Cancer (Reference)		Multivariable Adjusted Models, Cancer vs. No Cancer (Reference)
	Hazard Ratio (95% CI)	P Value	Hazard Ratio (95% CI)	P Value
All‐cause mortality	2.01 (1.96–2.06)	<0.001	1.44 (1.40–1.47)	<0.001
Cancer mortality	6.78 (6.48–7.10)	<0.001	5.33 (5.09–5.59)	<0.001
Cardiovascular events
Cardiovascular mortality	1.43 (1.39–1.48)	<0.001	1.03 (0.996–1.07)	0.085
Recurrent myocardial infarction	1.24 (1.20–1.28)	<0.001	1.08 (1.04–1.12)	<0.001
Admission for heart failure	1.51 (1.46–1.56)	<0.001	1.10 (1.06–1.13)	<0.001
Ischemic stroke	1.31 (1.23–1.40)	<0.001	1.01 (0.95–1.08)	0.708
Venous thromboembolism	1.90 (1.75–2.06)	<0.001	1.58 (1.46–1.72)	<0.001
Bleeding events
Fatal bleeding	1.85 (1.60–2.15)	<0.001	1.33 (1.15–1.55)	<0.001
Nonfatal major bleeding	2.02 (1.84–2.22)	<0.001	1.49 (1.35–1.64)	<0.001
Fatal bleeding or nonfatal major bleeding	1.98 (1.83–2.15)	<0.001	1.45 (1.34–1.57)	<0.001
Hospitalization for bleeding	1.80 (1.70–1.90)	<0.001	1.42 (1.34–1.51)	<0.001
Gastrointestinal bleeding	1.68 (1.58–1.79)	<0.001	1.35 (1.27–1.44)	<0.001
Hemorrhagic stroke	1.50 (1.31–1.71)	<0.001	1.16 (1.02–1.33)	0.029

Hazard ratios calculated using Cox proportional hazards models adjusted for age, sex, diabetes mellitus, hypertension, smoking status, previous heart failure, previous percutaneous coronary intervention, previous coronary artery bypass grafting, chronic kidney disease, peripheral arterial disease, indication for admission, previous stroke, year of admission, and percutaneous coronary intervention during hospitalization.