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. 2020 Feb 24;25(4):999. doi: 10.3390/molecules25040999

Scheme 6.

Scheme 6

a) 1,2,4-triazole, Na, CH3OH, reflux. b) NH2OH·HCl, C2H5OH, pH 14, reflux. c) R-COOH, DCC, DMAP, DCM, ethereal g HCl.