Scheme 33.
a) NH2NH2‚H2O, EtOH, reflux, quant. b) p-toluenesulfonyl chloride, Et3N, DCM, 67%. c) MnO2, CHCl3, reflux, 95%. d) Xylene, reflux, 67%. e) 4 N NaOH, MeOH, 65 °C, 85%. f) K2CO3, DMF, 5-chloromethyl-1-methyl-1H-1,2,4-triazole, 76%.
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