ADME |
Absorption, Distribution, Metabolism, and Excretion |
ACN |
Acetonitrile |
Bbt |
Barbiturate |
BZD |
Benzodiazepine(s) |
BZR |
Benzodiazepine receptor |
CDI |
1,1′-Carbonyldiimidazole |
DBU |
1,8-Diazabicyclo[5.4.0]undec-7-ene |
DCC |
N,N′-Dicyclohexylcarbodiimide |
DCE |
1,2-dichloroethane |
DCM |
Dichloromethane |
DMAc |
Dimethylacetamide |
DMAP |
4-Dimethylaminopyridine |
DMF |
Dimethylformamide |
DMSO |
Dimethyl sulfoxide |
DNA |
Deoxyribonucleic acid |
DEEMM |
Diethyl ethoxymethylenemalonate |
DIPEA |
N,N-Diisopropylethylamine |
EBOB |
Ethynylbicycloorthobenzoate |
ECD |
Extracellular domain |
Eto |
Etomidate |
GABA |
Gamma-aminobutyric acid |
GABAA
|
GABAA receptors |
HATU |
Hexafluorophosphate Azabenzotriazole Tetramethyl Uronium |
HTIB |
[Hydroxy(tosyloxy)iodo]benzene |
IPA HCl |
Isopropanol hydrochloride |
KOtBu |
Potassium tert-butoxide |
NAM |
Negative Allosteric Modulator |
NMP |
N-Methyl-2-Pyrrolidone |
OTC |
Over-the-counter |
PAM |
Positive Allosteric Modulator |
PET |
Positron Emmission Tomography |
PQ |
Pyrazoloquinolinone |
SAM |
Silent Allosteric Modulator |
TBBAB |
Tetra-n-butylammonium bromide |
TBAF |
Tetrabutylammonium fluoride |
TEA |
Triethylamine |
THF |
Tetrahydrofuran |
TMD |
Transmembrane domain |
TMP |
2,2,6,6-Tetramethylpiperidine |
TosMIC |
p-Toluenesulfonylmethyl isocyanide |