. 2020 Feb 18;25(4):903. doi: 10.3390/molecules25040903

Table 2.

In vitro susceptibilities of Candida isolates to DIMICAN and amphotericin B (AMB), determined by CLSI broth microdilution method. MICs were determined according to the CLSI M27-A3 using the partial (MIC_PI) and total inhibition (MIC_TI) criteria. [22]. MICs were read visually after 48 h incubation at 35 °C using the partial (50%) inhibition (for DIMICAN) (PI) and total inhibition (for AMB and DIMICAN) (TI) criteria. MICs were determined at least twice. DIMICAN = 1,1-N-dimethylamino-5-isocyanonaphthalene.

C. albicans				C. tropicalis				C. krusei
Isolate	MIC_PI (µg/mL)	MIC_TI (µg/mL)	AMB MIC_TI (µg/mL)	Isolate	MIC_PI (µg/mL)	MIC_TI (µg/mL)	AMB MIC_TI (µg/mL)	Isolate	MIC_PI (µg/mL)	MIC_TI (µg/mL)	AMB MIC_TI (µg/mL)
ATCC 10231	≤0.04	0.3	0.25	ATCC 750	0.15	1.25	0.5	ATCC 6258	0.15	0.3	1
456	≤0.04	0.6	0.5	579	0.08	0.6	0.5	749	0.08	0.08	1
665	≤0.04	0.6	1	622	0.08	0.3	1	1853	0.08	0.3	1
685	≤0.04	0.6	0.25	1776	0.08	0.3	1	4364	≤0.04	0.15	1
720	≤0.04	0.6	0.5	2467	0.15	1.25	0.5	5029	≤0.04	0.08	1
963	≤0.04	0.6	0.5	3014	0.08	0.6	0.5	5072	0.08	0.3	1
1544	≤0.04	0.6	0.25	5115	0.08	1.25	0.5	25504	0.08	0.3	0.5
8658	≤0.04	0.6	1	5806	0.08	0.15	0.25	34987	≤0.04	0.08	1
3666	≤0.04	0.6	0.5
*C. glabrata*				*C. parapsilosis*
Isolate	MIC_PI (µg/mL)	MIC_TI (µg/mL)	AMB MIC_TI (µg/mL)	Isolate	MIC_PI (µg/mL)	MIC_TI (µg/mL)	AMB MIC_TI (µg/mL)
ATCC 90030	0.15	0.3	0.5	ATCC 22019	0.15	0.6	0.5
14408	≤0.04	0.08	0.5	4133	0.08	0.08	0.25
14559	≤0.04	0.3	0.5	9613	0.15	0.15	0.25
22394	≤0.04	0.3	0.5	10252	≤0.04	0.08	0.5
23429	≤0.04	0.3	1	18154	0.08	0.6	0.5
23481	0.08	1.25	1	27001	≤0.04	0.3	0.25
27643	0.08	0.3	0.5
28557	≤0.04	0.6	0.5