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. 2020 Feb 4;9(2):137. doi: 10.3390/antiox9020137

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Post-treatment with erinacine A reversed the PAK1/AKT/LIMK2/ pathways in the MPTP-treated animals. Representative IHC images of p-PAK1, p-cdc42, p-PI3K p110, p-AKT, and p-LIMK2 in the brain region of the animals with MPP⁺ or MPP⁺ and erinacine A are as indicated. Quantified data of the average integral optical density are expressed as the mean ± SEM (fold increase of untreated animals). Data are expressed as mean ± S.D. (n = 6/group); * p < 0.01, as compared to the control group; # p < 0.01, as compared to the MPP⁺-treated group.