. 2020 Jan 26;9(2):107. doi: 10.3390/antiox9020107

Table 3.

Studies exploring PTSD- and oxidative stress-related genetic markers in PTSD.

Trauma Types	Genetic Marker	N (m/f)	Altered Direction	Main Findings	Ref.
Combat	BDNF	461 (413/48)	Increase	- Individuals with PTSD had higher frequencies of Met/Met and 66Met allele than individuals without PTSD.	[75]
	Val66Met
	(rs6265)
	BDNF	257 (257/0)	None	- Individuals had similar frequencies of Met/Met and 66Met allele as resilience trauma-exposed individuals.	[76]
	Val66Met
	(rs6265)
Other	RORA	435 (260/175)	N/A	- A significant association was reported between a RORA SNP (rs8042149) and PTSD diagnosis.	[77]
Other	SNPs	435 (260/175)	N/A		[77]
	RORA	551 (193/358)	N/A	- A significant association was reported between a RORA SNP (rs8042149) and PTSD diagnosis.	[78]
	SNPs	551 (193/358)	N/A		[78]

Abbreviations: BDNF, brain-derived neurotrophic factor; m, male; N, sample size; N/A, not applicable; PTSD, post-traumatic stress disorder; Ref., reference; SNP, single nucleotide polymorphism.