Table 5.
IC50 of extracts on KYSE 70 and SiSo cell lines in secondary screening.
| Extract | Cell Line | |
|---|---|---|
| KYSE 70 | SiSo | |
| IC50 (µg/mL) | ||
| DLEc | 11.03 ± 2.68 | 12.06 ± 8.39 |
| DSbEc | 2.26 ± 0.92 | 6.37 ± 2.15 |
| DLEh | 12.23 ± 3.12 | 10.68 ± 2.36 |
| DSbEh | 5.28 ± 3.43 | 5.62 ± 3.00 |
| MLEc | >50 | 11.01 ± 4.04 |
| MSbEc | >50 | 23.85 ± 9.41 |
| MLEh | >50 | 20.93 ± 4.09 |
| MSbEh | >50 | >50 |
Stock solution concentration = 50 µg/mL DMSO for DLEh, DSbEh, MLEc, MSbEc, MLEc and MSbEh, 25 µg/mL DMSO for DLEc and DSbEc. n = 3; DLEc—cold DCM leaf extract, DSbEc—cold DCM stem bark extract, DLEh—hot DCM leaf extract, DSbEh—hot DCM stem bark extract, MLEc—cold methanol leaf extract, MSbEc—cold methanol stem bark extract, MLEh—hot methanol leaf extract, MSbEh—hot methanol stem bark extract, WLEc—cold water leaf extract, WSbEc—cold water stem bark extract, WLEh—hot water leaf extract and WSbEh—hot water stem bark extract.