mRNA expression of heat shock protein genes and the oxidative stress-responsive FOXO gene in C. elegans grown under normal temperature conditions (20 °C) or under heat stress (37 °C) without (control) or with the addition of ginseng extract. The final concentration of ginsenosides was 135 mg/L (Gin 135.0). The expression levels of hsp-1 (A), daf-16 (B) and hsp-16.2 (C) are indicated as the fold-change normalized to the control under the normal temperature condition of 20 °C. Error bars are based on the standard deviation (n = 6 (A), n = 9 (B,C)). **** p < 0.0001, *** p < 0.001, ** p < 0.01 and * p < 0.05 indicate significant differences from the control under 37 °C heat stress conditions.