SKE attenuated airway inflammation and mucus production during OVA-induced allergic airway inflammation. Lung tissue samples were stained with hematoxylin and eosin (H and E) and Diff-Quik agents. (a) Airway inflammation and (b) mucus production. The quantitative analysis of airway inflammation and mucus production were measured by an image analyzer. NC, PBS treatment and PBS sensitization/challenge; OVA, PBS treatment and OVA sensitization/challenge; Mon: montelukast treatment and OVA sensitization/challenge; SKE 20 and 40, SKE treatment (20 and 40 mg/kg, respectively) and OVA sensitization/challenge. Scale bars indicate 50 μm. Values are shown as the mean ± SD (n = 5). ## p < 0.01 versus NC; *,** p < 0.05 and 0.01 versus OVA.