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. 2020 Jan 24;9(2):99. doi: 10.3390/antiox9020099

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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SKE reduced HO-1 expression in the lungs during OVA-induced allergic airway inflammation. The expression of HO-1 on lung tissue was determined by IHC. NC, PBS treatment and PBS sensitization/challenge; OVA, PBS treatment and OVA sensitization/challenge; Mon: montelukast treatment and OVA sensitization/challenge; SKE 20 and 40, SKE treatment (20 and 40 mg/kg, respectively) and OVA sensitization/challenge. Scale bars indicate 50 μm. Values are shown as the mean ± SD (n = 5). ## p < 0.01 versus NC; * p < 0.05 versus OVA.