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. 2019 Nov 29;13(2):325–336. doi: 10.1111/cts.12713

Figure 3.

Figure 3

Arithmetic mean (SD) of % Bruton's tyrosine kinase (BTK) receptor occupancy* vs. time after administration of evobrutinib for (a) single dosing and (b) multiple dosing. *% BTK occupancy = (1‐(BTKF/BTKT)/(BTKF pre‐dose/BTKT pre‐dose))*100. BTKT, total Bruton's tyrosine kinase; BTKF, free Bruton's tyrosine kinase.