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. 2020 Feb 14;25(4):845. doi: 10.3390/molecules25040845

Table 1.

Parameters of EPR spectra, octanol–water partition coefficients (Kp), and rate constants of reduction with ascorbate for nitroxides 1, 2, 4, and 5 (for details, see the experimental part).

Nitroxide Solvent Parameters of EPR Spectra Kp (Octanol–H2O) kRed × 104, M−1c−1
aN, mT aH, mT Hp-p, mT
1 H2O 1.56 0.2 0.125 - 12.5 ± 0.3
20 ± 10 [19]
H2O-MeOH 1:1 1.52 0.202 0.6 ± 0.2
2 H2O 1.527 0.225 0.12 3.8 ± 0.5
3.3 ± 0.8 [20]
H2O-MeOH 1:1 1.493 0.198 1.2 ± 0.1
4 H2O 1.605 0.214 0.124 1000 ± 250 -
H2O-MeOH 1:1 1.529 0.199 1.7 ± 0.1
5 H2O 1.586 0.251 0.117 850 ± 120 -
H2O-MeOH 1:1 1.498 0.248 0.012 ± 0.03