Figure 1.

Establishment of streptozotocin (STZ)-induced diabetic mice. The mice with blood glucose greater than 16.7 mmol/L were defined as diabetic mice. (A) Chemical structures of curcumin and C66. Blood glucose levels (B) were monitored during the study period. Body weight (C) was significantly decreased in the diabetic group and C66 treatment group compared with the control group. The data are expressed as the means ± S.D. (n = 6 per group, ** p < 0.01 compared to the control value). DM and Ctrl are short for the diabetic and control group, respectively.