. 2020 Mar 6;37(6):889–898. doi: 10.1089/neu.2019.6731

Table 3.

1-DPI and 30-DPI MRI Metrics as Predictors for 90-DPI BBB Score

		90-dpi BBB		90-dpi BBB (sham excluded)
Time point	Metric	R²	p value	R²	p value
1 dpi	fADC_\|\| DDE-PRESS	0.375	<0.001^*	0.436	0.001^*
	fADC_\|\| image based	0.219	0.009^*	0.049	0.320
	AWF	0.000	0.943	0.011	0.654
	T₂	0.069	0.161	0.210	0.032^*
	CSA	0.001	0.884	0.029	0.446
	Hemorrhage area	0.031	0.354	0.110	0.131
30 dpi	fADC_\|\| DDE-PRESS	0.246	0.006^*	0.197	0.050^*
	fADC_\|\| image based	0.462	0.001^*	0.270	0.047^*
	AWF	0.644	<0.001^*	0.533	0.003^*
	T₂	0.178	0.040^*	0.067	0.333
	CSA	0.415	0.001^*	0.291	0.031^*
	Hemorrhage area	0.001	0.915	0.109	0.211

^{^*}

Indicates significance of p < 0.05.

dpi, days post-injury; MRI, magnetic resonance imaging; BBB, Basso, Beattie, and Bresnahan; fADC_||, “filtered” parallel diffusivity from imaged-based DDE; DDE, double-diffusion encoding; PRESS, point-resolved single-voxel spectroscopy; AWF, axonal water fraction; CSA, cross-sectional area;