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. 2020 Feb 11;25(4):770. doi: 10.3390/molecules25040770

Table 1.

Results of the in vitro cytotoxic activity of benzimidazoles against the HepG2 cell line.

Entry Compound IC50 (μM) a on HepG2 Cell Line
1 4a > 200
2 4b 102.54
3 6 13.52
4 8a > 200
5 8b > 150
6 8c > 200
7 8d > 150
8 9a 32.53
9 10a 301.35
10 13a 158.14
11 13b 136.84
12 13c 140.11
13 13d 11.93
14 13e 86.97
15 13f 16.67
16 13g 13.90
17 13h 59.85
18 14a 25.88
19 14b 26.16
20 14c 112.35
21 14d 62.00
22 17a 1.98
23 17b 10.04
24 17c 20.18
25 17d 15.55
26 17e 24.11
27 17f 42.49
28 19a 109.47
29 19b 71.73
30 19c 133.39
31 19d 114.17
32 22a 122.93
33 22b 106.88
34 24a 80.68
35 24b 15.92
36 24c 8.73
37 Sorafenib (I) 10.99

a IC50 are presented as mean of three independent experiments.