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. 2020 Mar 6;37(6):860–867. doi: 10.1089/neu.2019.6694

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© Maryam Seif et al., 2019; Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.

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FIG. 3. — Voxel-wise analysis of microstructural changes above the level of injury (C2/C3 level) overlaid on the averaged fractional anisotropy maps across subjects in traumatic spinal cord injury (SCI) patients compared with degenerative cervical myelopathy (DCM) patients. (A) white matter atlas and hyperintensity signal on the T2*-weighted scan of a tSCI patient; (B and C) Decreased axial diffusivity (AD) in both SCI groups (American Spinal Injury Association Impairment Scale [AIS] A&B, p = 0.005; AIS C&D, p < 0.001) in dorsal columns and corticospinal tract compared with DCM patients. (D) Decreased fractional anisotropy (FA) in SCI group with AIS A&B grade compared with DCM patients in dorsal columns (p < 0.001). For illustration purpose, the displayed t values are uncorrected at the threshold of p = 0.01. Color image is available online.