Table 2.
Clinical Features and Outcomes in Enterococcus Bacteremia
All Patients | No IDC | IDC | ||
---|---|---|---|---|
(n = 205) | (n = 74) | (n = 131) | P Value | |
Repeat cultures | 185 (90) | 55 (74) | 130 (99) | <.001 |
Echocardiogram performed | 136 (66) | 33 (45) | 103 (79) | <.001 |
Unknown primary source | 65 (32) | 40 (54) | 25 (19) | <.001 |
Primary source (among known) | ||||
• Intravascular catheter | 43 (21) | 7 (10) | 36 (28) | .016 |
• Skin/soft tissue | 7 (3) | 4 (5) | 3 (2) | |
• GI | 29 (14) | 8 (10) | 21 (16) | |
• Bone and joint | 6 (3) | 0 (0) | 6 (5) | |
• Endocarditis | 17 (8) | 0 (0) | 17 (13) | |
• Urinary tract | 21 (10) | 9 (12) | 12 (9) | |
• Other | 14 (7) | 6 (8) | 8 (6) | |
Removal of catheter | 34 (16) | 6 (75) | 28 (70) | 1.00 |
Time to definitive antibiotics, median (IQR), d | 0 (2) | 0 (1) | 1 (2) | .30 |
Inappropriate antibiotic duration | 53 (26) | 40 (54) | 13 (10) | <.001 |
Inappropriate or no antibiotics | 14 (7) | 14 (19) | 0 (0) | <.001 |
Treatment failure | 15 (7) | 8 (11) | 7 (5) | .12 |
Surgical intervention | 31 (15) | 5 (7) | 26 (20) | .01 |
Recurrent bacteremia within 60 d | 10 (5) | 5 (7) | 5 (4) | .50 |
Readmission within 60 d | 67 (41) | 24 (42) | 43 (40) | .81 |
30-d mortality | 36 (18) | 20 (27) | 16 (12) | .007 |
90-d mortality | 56 (27) | 25 (34) | 31 (24) | .12 |
LOS, median (IQR), d | 14.5 (32) | 11 (27) | 18 (35) | .09 |
Postbacteremia LOS, median (IQR), d | 10.5 (16) | 10.5 (15) | 10.5 (22) | .004 |
Abbreviations: GI, gastrointestinal; IDC, infectious diseases consultation; IQR, interquartile range; LOS, length of stay.