Table 3.
Serum biochemical results of vehicle control and treated Swiss albino mice (mean ± SD).
| Blood Index | Male | Female | ||||||
|---|---|---|---|---|---|---|---|---|
| Vehicle Control | OC-10 mg/kg | OC-250 mg/kg | OC-500 mg/kg | Vehicle Control | OC-10 mg/kg | OC-250 mg/kg | OC-500 mg/kg | |
| GLU (mg/dL) | 95.0 ± 10.0 | 240.5 ± 4.5 * | 236.0 ± 27.0 * | 185.5 ± 12.5 * | 205.0 ± 1.0 | 235.0 ± 1.0 | 205.0 ± 11.0 | 274.0 ± 28.5 * |
| AST (U/L) | 173.5 ± 15.5 | 165.0 ± 76.0 * | 93.5 ± 17.5 * | 100.0 ± 6.0 * | 158.5 ± 10.5 | 128.0 ± 7.0 * | 174.5 ± 0.0 | 145.5 ± 13.5 |
| ALT (U/L) | 62.0 ± 2.0 | 35.5 ± 12.5 * | 25.0 ± 7.0 * | 33.0 ± 8.0 * | 53.0 ± 14.0 | 36.5 ± 1.5 | 41.0 ± 5.0 | 32.5 ± 2.5 * |
| ALP (U/L) | 15.0 ± 3.0 | 6.0 ± 1.0 * | 5.5 ± 0.5 * | 7.0 ± 1.0 * | 7.5 ± 2.5 | <5.0# | 7.5 ± 2.5 | 7.5 ± 2.5 |
| BUN (mg/dL) | 36.0 ± 5.0 | 21.5 ± 0.5 * | 22.0 ± 1.0 * | 21.5 ± 0.5 * | 21.5 ± 1.5 | 23.0 ± 0.0 | 26.0 ± 1.0 * | 24.5 ± 1.5 * |
| CREAT (mg/dL) | <0.2# | <0.2# | <0.2# | <0.2# | <0.2# | <0.2# | <0.2# | <0.2# |
* Indicate statistically significant difference at p < 0.05, (#) < dL = detection limit.