Figure 2.

Contractile response of rat thoracic arteries to noradrenaline (NA, 0.1 μM) (a–f). The effect obtained under (a) control conditions; (b) with nitric oxide synthase inhibitor (l-NAME, 100 μM, 30 min) and (c) with the nonselective cyclooxygenase inhibitor (indomethacin, 10 μM, 30 min) on NA-induced contractions. From the 8^th week of age, rats were supplemented for 4 weeks with either dandelion leaf fraction (LF) or petal fraction (PF). The control group was not supplemented with dandelion. Results are expressed as mean ± SEM, n = 6. * p ≤ 0.05 (two-way ANOVA/Tukey’s). Abbreviations: CC, control conditions; Indo, Indomethacin and l-NAME, N(ω)-nitro-l-arginine methyl ester.