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. 2020 Feb 3;9(2):131. doi: 10.3390/antiox9020131

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The cumulative concentration-response curves to acetylcholine (a) in control rats, (b) in rats supplemented with dandelion leaf fraction (LF) and (c) in dandelion petal fraction (PF)-fed rats. The aortic rings were preincubated either with nitric oxide synthase inhibitor (l-NAME, 100 μM, 30 min) or the nonselective cyclooxygenase inhibitor (indomethacin, 10 μM, 30 min). Results (mean ± SEM, n = 6) are expressed as a percentage of inhibition of the contraction induced by NA (0.1 μM), p ≤ 0.05 (two-way ANOVA/Tukey’s). Abbreviations: CC, control conditions; Indo, Indomethacin and l-NAME, N(ω)-nitro-l-arginine methyl ester.