Table 2.
Effects of sesamol (SEM) on serum metabolic parameters.
| NFD | HFD | HFD+SEM | |
|---|---|---|---|
| Serum TG (mM) | 0.74 ± 0.10 | 1.59 ± 0.42 * | 0.93 ± 0.17 # |
| Serum TC (mM) | 5.90 ± 0.96 | 13.38 ± 3.03 * | 10.03 ± 0.93 # |
| Serum LDL-C (mM) | 0.16 ± 0.03 | 0.24 ± 0.03 * | 0.18 ± 0.03 # |
| Serum HDL-C (mM) | 2.43 ± 0.55 | 2.53 ± 0.15 | 3.79 ± 0.15 *# |
| Serum FFA (μM) | 66.69 ± 2.82 | 76.07 ± 3.40 * | 63.07 ± 2.62 # |
| Serum β-HB (mM) | 0.14 ± 0.02 | 0.11 ± 0.01 * | 0.13 ± 0.01 # |
| Serum TNF-α (pg/mL) | 11.79 ± 0.78 | 13.92 ± 1.72 * | 11.17 ± 0.73 # |
| Serum IL-6 (pg/mL) | 11.07 ± 0.61 | 14.8 ± 1.98 * | 12.07 ± 1.12 # |
All values are presented as mean ± SD (n = 5). * p < 0.05 versus the NFD group; # p < 0.05 versus the HFD group. NFD: normal-fat diet group, HFD: high-fat diet group, HFD+SEM: HFD+SEM group, TG: triacylglycerol, TC: total cholesterol, LDL-C: low-density lipoprotein cholesterol, HDL-C: high-density lipoprotein cholesterol, ALT: alanine aminotransferase, AST: aspartate aminotransferase, FFA: free fatty acid, β-HB: β-hydroxybutyrate, TNF-α: tumor necrosis factor-α, IL-6: interleukin-6.