Table 3.
Effect of diet advice interventions in women with gestational diabetes on the risk of maternal medication use, on gestational weight gain (GWG), on the growth at birth and on the risk of neonatal hypoglycaemia according to meta-analyses. Values are in bold when the results were statistically significant; p values are indicated when they were reported in the reviews. LGA: Large for Gestational Age.
MOTHER | NEONATE | ||||||
---|---|---|---|---|---|---|---|
N | Medication RR [95% CI] |
GWG kg Mean [SD] |
LGA RR [95% CI] |
Macrosomia RR [95% CI] |
Birth Weight g Mean [SD] |
Hypoglycaemia RR [95% CI] |
|
Viana 2014 [32] | |||||||
Low glycemic index | 257 |
0.77
[0.66, 0.99] ** |
−0.41 [−1.84, 1.02] |
ND | 0.48 [0.15, 1.56] |
−161.9 [−246.4, −77.4] ¶ |
ND |
Energy restriction diet | 425 | ND | ND | ND | 1.00 [0.65, 1.55] |
ND | 1.01 [0.72, 1.43] |
Low carbohydrates | 182 | 1.06 [0.15, 1.56] |
ND | ND | 0.35 [0.06, 1.91] |
ND | ND |
Wei 2016 [33] | |||||||
Low glycemic index | 302 | 0.67 [0.44–1.00] * |
ND | 1.38 [0.58, 3.32] |
0.27 [0.10, 0.71] § |
ND | ND |
Han 2017 [34] | |||||||
Low glycemic index | 224 | 0.82 [0.39, 1.74] |
−0.47 [−2.18, 1.24] |
0.71 [0.22, 2.34] |
0.59 [0.16, 2.26] |
−56.0 [−201.9, 89.9] |
ND |
Energy restriction diet | 437 | 1.05 [0.47, 2.34] |
+1.88 [−1.96, 5.72] |
1.17 [0.65, 2.21] |
0.99 [0.64, 1.53] |
−107.0 [−240.3, 26.3] |
1.06 [0.48, 2.32] |
Low carbohydrates | 182 | 1.02 [0.77, 1.37] |
−0.90 [−1.60, −0.20] |
0.51 [0.13, 1.95] |
0.20 [0.02, 1.69] |
+ 22.0 [−241.1, 285.1] |
0.91 [0.39, 2.12] |
DASH diet | 136 | 0.28 [0.14, 0.53] ** |
−2.88 [−8.48, −2.71] |
ND | 0.10 [0.01, 0.73] |
−581.3 [−790.3, −372.2] |
ND |
Yamamoto 2018 [35] | |||||||
All diet | 1023 | 0.65 [0.47, 0.88] |
ND | 0.96 [0.63, 1.46] |
0.49 [0.27, 0.88] ** |
−171.6 [−333.6, −7.6] ** |
ND |
Low glycemic index | 0.80 [0.55, 1.14] |
ND | 1.33 [0.54, 3.31] |
0.46 [0.15, 1.46] |
−54.2 [−179.0, 70.5] |
ND | |
Energy restriction diet | 1.05 [0.47, 2.34] |
ND | 1.17 [0.65, 2.12] |
1.56 [0.61, 3.94] |
194.0 [−42.6, 430.6] |
ND | |
Low carbohydrates | 1.00 [0.75, 1.34] |
ND | 0.51 [0.13, 1.95] |
0.20 [0.02, 1.69] |
57.7 [−164.9, 280.4] |
ND |
* p = 0.05; ** p < 0.05; § p ≤ 10−2; ¶ p ≤ 10−3.